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Example Input Mode:
Partner Data
CBIS
Matrix
Example Data Type:
Secondary Screen (Kd)
Primary Screen(% control or competition)
If the input file contains Primary and Secondary Data, use:
Primary
Secondary
Assay Data File:
.txt or .csv format - download examples:
Bromodomain
Kd
Primary
To highlight spots, select a compound(s), click 'fill' and select entries.
Create Images for:
MLN-8054
Highlight These Spots (
fill
):
MLN-8054|ABL1-nonphosphorylated|1100
MLN-8054|ABL2|3300
MLN-8054|AURKA|6.5
MLN-8054|AURKB|43
MLN-8054|AURKC|26
MLN-8054|AXL|440
MLN-8054|BLK|68
MLN-8054|BMX|3100
MLN-8054|BTK|4200
MLN-8054|CLK2|3200
MLN-8054|CLK3|2300
MLN-8054|CSK|9000
MLN-8054|DAPK2|9100
MLN-8054|DDR1|4200
MLN-8054|DRAK1|190
MLN-8054|DRAK2|8.1
MLN-8054|EPHA1|1800
MLN-8054|EPHA2|370
MLN-8054|EPHA3|2100
MLN-8054|EPHA4|420
MLN-8054|EPHA5|1400
MLN-8054|EPHA6|580
MLN-8054|EPHA7|1000
MLN-8054|EPHB1|330
MLN-8054|EPHB3|3500
MLN-8054|EPHB4|560
MLN-8054|FER|4400
MLN-8054|FGFR1|2400
MLN-8054|FGFR2|1700
MLN-8054|FGFR3|1200
MLN-8054|FGR|220
MLN-8054|FLT1|1000
MLN-8054|FLT4|3100
MLN-8054|FYN|1300
MLN-8054|HCK|1500
MLN-8054|IRAK3|1400
MLN-8054|LCK|590
MLN-8054|LOK|3700
MLN-8054|LYN|1400
MLN-8054|MERTK|730
MLN-8054|PLK4|410
MLN-8054|PYK2|2000
MLN-8054|ROS1|3100
MLN-8054|RSK1(Kin.Dom.1-N-terminal)|4800
MLN-8054|SIK|1700
MLN-8054|SRC|800
MLN-8054|TEC|730
MLN-8054|TIE1|1600
MLN-8054|TIE2|300
MLN-8054|TNK1|2400
MLN-8054|TYRO3|3100
MLN-8054|YES|260
MLN-8054|ABL1-nonphosphorylated
MLN-8054|ABL2
MLN-8054|AURKA
MLN-8054|AURKB
MLN-8054|AURKC
MLN-8054|AXL
MLN-8054|BLK
MLN-8054|BMX
MLN-8054|BTK
MLN-8054|CLK2
MLN-8054|CLK3
MLN-8054|CSK
MLN-8054|DAPK2
MLN-8054|DDR1
MLN-8054|DRAK1
MLN-8054|DRAK2
MLN-8054|EPHA1
MLN-8054|EPHA2
MLN-8054|EPHA3
MLN-8054|EPHA4
MLN-8054|EPHA5
MLN-8054|EPHA6
MLN-8054|EPHA7
MLN-8054|EPHB1
MLN-8054|EPHB3
MLN-8054|EPHB4
MLN-8054|FER
MLN-8054|FGFR1
MLN-8054|FGFR2
MLN-8054|FGFR3
MLN-8054|FGR
MLN-8054|FLT1
MLN-8054|FLT4
MLN-8054|FYN
MLN-8054|HCK
MLN-8054|IRAK3
MLN-8054|LCK
MLN-8054|LOK
MLN-8054|LYN
MLN-8054|MERTK
MLN-8054|PLK4
MLN-8054|PYK2
MLN-8054|ROS1
MLN-8054|RSK1(Kin.Dom.1-N-terminal)
MLN-8054|SIK
MLN-8054|SRC
MLN-8054|TEC
MLN-8054|TIE1
MLN-8054|TIE2
MLN-8054|TNK1
MLN-8054|TYRO3
MLN-8054|YES
MLN-8054|ABL1-nonphosphorylated|1100
MLN-8054|ABL2|3300
MLN-8054|AURKA|6.5
MLN-8054|AURKB|43
MLN-8054|AURKC|26
MLN-8054|AXL|440
MLN-8054|BLK|68
MLN-8054|BMX|3100
MLN-8054|BTK|4200
MLN-8054|CLK2|3200
MLN-8054|CLK3|2300
MLN-8054|CSK|9000
MLN-8054|DAPK2|9100
MLN-8054|DDR1|4200
MLN-8054|DRAK1|190
MLN-8054|DRAK2|8.1
MLN-8054|EPHA1|1800
MLN-8054|EPHA2|370
MLN-8054|EPHA3|2100
MLN-8054|EPHA4|420
MLN-8054|EPHA5|1400
MLN-8054|EPHA6|580
MLN-8054|EPHA7|1000
MLN-8054|EPHB1|330
MLN-8054|EPHB3|3500
MLN-8054|EPHB4|560
MLN-8054|FER|4400
MLN-8054|FGFR1|2400
MLN-8054|FGFR2|1700
MLN-8054|FGFR3|1200
MLN-8054|FGR|220
MLN-8054|FLT1|1000
MLN-8054|FLT4|3100
MLN-8054|FYN|1300
MLN-8054|HCK|1500
MLN-8054|IRAK3|1400
MLN-8054|LCK|590
MLN-8054|LOK|3700
MLN-8054|LYN|1400
MLN-8054|MERTK|730
MLN-8054|PLK4|410
MLN-8054|PYK2|2000
MLN-8054|ROS1|3100
MLN-8054|RSK1(Kin.Dom.1-N-terminal)|4800
MLN-8054|SIK|1700
MLN-8054|SRC|800
MLN-8054|TEC|730
MLN-8054|TIE1|1600
MLN-8054|TIE2|300
MLN-8054|TNK1|2400
MLN-8054|TYRO3|3100
MLN-8054|YES|260
clear
Select Highlight spots color from Pallette:
(also used in table view)
Tree Image Options
Restore default options
Spot options:
IndianRed
PaleGreen
Gold
PowderBlue
Fill?
Outline?
Outline thickness:
1
2
3
4
5
Select Spots Color from Pallette:
(spot highlight color below)
micro
nano
Spot Size:
Scaling Factor:
.1
.2
.3
.4
.5
.6
.7
.8
.9
1
1.1
1.2
1.3
Area increase factor:
100%
90%
80%
70%
60%
50%
(per change of 10x Kd or 10% Competition)
Legend options:
Left align Text
Right align Text
Label options:
Compound Name?
Compound Name Font:
.5
1
1.5
2
Show Assay Panel information?
Show Panel Spots?
Append Concentration? (i.e., 'AB500@1000nm'; check before loading.)
Background Image:
Target labels?
Dark Tree Branch image?
Hide Lipid, Mutant, ATypical and Pathogen?
Spot options:
Spot Color transparency level:
none
low
medium-low
medium
high
no color
Spot Cutoff Value:
Kd (nM) (Blank for no cutoff)
Spot outline only?
Format:
JPEG(200KB per image)
Publication Quality(5MB image)
Create Publication Quality (5MB bitmap) Image for:
Select Compound
MLN-8054
size/quality
100
90
80
70
60
50
40
30
% of original
White Space Border:
Yes
No
Preview and Highlighting
Highlight an assay by clicking on the spot or checking the box next to the Gene Symbol Name.
Click 'Update' to create the new images.
Compound To Highlight:
None
MLN-8054
Highlight Panel?
* WildType kinase assays appear in both the main TREEspot and Mutant kinase dendrogams.
Human Kinome image created by KINOMEscan.
2 images created. To download (copy and paste) all images to your local machine click Open/Browse Image Folder.
Images Saved To:
D:\Eurofins\PROD\Applications\FrontOffice_Discovery\StudyManagement\TreeSpot\HTSTools\TreeImages\758_pjesr4mg0xvtpxxd2apuohmw\
Open/Browse Image Folder
View Options:
(These options do not modify the images that have been created, only the view on this page)
MLN-8054
Legend
Show Selected
Size:
Select Size
small
medium
full size
Images per Row:
1
Legend Resize?
Hover the cursor to identify spots and click to highlighted it. To save an image click the Zoom/Download link.
Zoom/Download
Highlight
Locate an Assay
ABL1-nonphosphorylated
ABL1-nonphosphorylated
AURKA
AURKB
AURKC
AXL
BLK
CLK3
DRAK1
DRAK2
EPHA1
EPHA2
EPHA3
EPHA4
EPHA5
EPHA6
EPHA7
EPHB1
EPHB4
FGFR1
FGFR2
FGFR3
FGFR3
FGR
FLT1
FYN
HCK
IRAK3
LCK
LYN
MERTK
PLK4
PYK2
SIK
SRC
TEC
TIE1
TIE2
TNK1
YES
Legend
Data Table View:
Show All Data
Only Selected Compounds/Trees
TREE
spot
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